Just installed wine on my Mac side on the same machine (running also Windows via bootcamp)
Also using pure and up-to-date Wine, Sculptris runs on a Mac OS X (10.6.3)
Also here, Sculptris sculpt works without any restriction. I´m gonna to compare the performance in the next hours to the Windows installation. Just a minor problem starting the app: The GUI appears with a offset in the window, but deminishing and maximize put s this right.
Also here: no shaders have to be set in the config.txt So as letoatrell reported, paint also works here, but without material/multimaterial and bumpmapping
Being new to wine: How to fix the keyboard shortcuts?